CHEMBL5747372


SMILES O=S(=O)(N[C@H]1CC[C@@H](CCN2CCN(c3nsc4ccccc34)CC2)CC1)c1cccs1
InChIKey UCRMCTXHTPNGTQ-KDURUIRLSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 490.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.35 8.46 8.67 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.12 9.24 9.3 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.76 8.76 8.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database