CHEMBL5647639


SMILES CCC(Oc1cc(Cl)cc(Cl)c1)c1nc(Nc2ccncc2)nc(N2CCN(C)CC2)n1
InChIKey CYTWSFCTEHSEGC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 473.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.9 4.9 4.9 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.18 7.18 7.18 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.31 5.31 5.31 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.36 6.36 6.36 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.14 6.14 6.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database