CHEMBL5647099


SMILES CCC(Oc1cc(C(F)(F)F)ccc1C(F)(F)F)c1nc(N)nc(N2CCN(C)CC2)n1
InChIKey YDDRYYASSGIIFK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 464.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.74 4.74 4.74 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.07 5.07 5.07 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.81 5.81 5.81 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.09 6.09 6.09 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database