CHEMBL5639487


SMILES CC(Oc1cc(F)ccc1F)c1nc(N)nc(N2CCN(C)CC2)n1
InChIKey KYTWKFPFQDRWHN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 350.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.66 4.66 4.66 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.25 7.25 7.25 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.51 5.51 5.51 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.64 5.64 5.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.99 5.99 5.99 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database