CHEMBL5639353


SMILES CCCCC(Oc1cc(Cl)cc(Cl)c1)c1nc(Nc2ccccc2)nc(N2CCN(C)CC2)n1
InChIKey NZJUYULZIBPYPQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 500.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.47 4.47 4.47 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.68 7.68 7.68 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.54 6.54 6.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.59 5.59 5.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database