CHEMBL5639113


SMILES CCC(Oc1cc(F)ccc1OC)c1nc(N)nc(N2CCN(C)CC2)n1
InChIKey ZKZMECIDSBGYIC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 376.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.35 4.35 4.35 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.14 7.14 7.14 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.32 5.32 5.32 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.09 6.09 6.09 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.75 5.75 5.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database