PRUVANSERIN


SMILES N#Cc1c[nH]c2c(C(=O)N3CCN(CCc4ccc(F)cc4)CC3)cccc12
InChIKey AQRLDDAFYYAIJP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 376.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.23 6.23 6.23 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.62 5.62 5.62 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.74 6.74 6.74 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.98 5.98 5.98 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.58 8.95 9.32 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.83 6.01 6.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database