CHEMBL5633074


SMILES CCC(Sc1cc(Cl)ccc1Cl)c1nc(N)nc(N2CCN(C)CC2)n1
InChIKey IHJUENPGSBRDEB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 412.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.29 5.29 5.29 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.26 6.26 6.26 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.0 6.0 6.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pEC50 6.81 6.81 6.81 ChEMBL