CHEMBL5632924


SMILES CN1CCN(c2nc(N)nc(C(C)(C)Oc3ccccc3Cl)n2)CC1
InChIKey KJEOOSAJFDVYPE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 362.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.25 5.25 5.25 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.1 7.1 7.1 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.24 6.24 6.24 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.1 6.1 6.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database