CHEMBL5632197


SMILES CCC(Sc1cc(Cl)cc(Cl)c1)c1nc(N)nc(N2CCN(C)CC2)n1
InChIKey PJJRJAVZONAJSD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 412.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.22 5.22 5.22 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.99 6.99 6.99 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.44 6.44 6.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database