CHEMBL5631694


SMILES CCC(Sc1cccc(Cl)c1Cl)c1nc(N)nc(N2CCNCC2)n1
InChIKey CHDMODINJRXNKV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 398.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.48 5.48 5.48 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.73 6.73 6.73 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.94 6.94 6.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pEC50 6.45 6.45 6.45 ChEMBL