CHEMBL5594872


SMILES Cc1ncc(S(=O)(=O)N2CCC(c3cn4ncnc4cc3Cl)CC2)o1
InChIKey URAUBDCJGRESTK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 381.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Mouse Acetylcholine (muscarinic) A pIC50 7.33 7.53 7.72 ChEMBL
M5 ACM5 Rat Acetylcholine (muscarinic) A pIC50 7.29 7.38 7.46 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A pIC50 5.58 5.58 5.59 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pIC50 7.68 7.69 7.7 ChEMBL