HEAT (BE2254)


SMILES Oc1ccc(c(c1)[125I])CCNCC1CCc2c(C1=O)cccc2
InChIKey MIQRUWUVLIWVAW-STTHPYEQSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 419.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 8.6 8.6 8.6 Guide to Pharmacology
α1B ADA1B Human Adrenoceptors A pKd 8.0 8.0 8.0 Guide to Pharmacology
α1D ADA1D Human Adrenoceptors A pKd 9.5 9.5 9.5 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database