CHEMBL5571457


SMILES CC1=CC[C@@H]2C[C@H]1[C@H](c1ccc(C(F)(F)F)c(F)c1)NC2(C)C
InChIKey JWBACCHTZDUJCB-IOASZLSFSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 327.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.0 6.0 6.0 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.55 5.55 5.55 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.28 6.28 6.28 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.24 6.24 6.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database