CHEMBL5558071


SMILES O=C1CN2c3c(cccc3[C@@H]3CN(CCCc4n[nH]c5cc(F)ccc45)CC[C@@H]32)N1
InChIKey IYWYHDLOCSDKEQ-UWJYYQICSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 405.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 8.28 8.28 8.28 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.59 8.59 8.59 ChEMBL
μ OPRM Human Opioid A pKi 7.41 7.41 7.41 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.82 7.82 7.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database