CHEMBL5465172


SMILES O=C1NCCCC1N1Cc2cc(C3CCN(C(=O)CCCCCN4CCC(c5ccc(Oc6nn7cnnc7c7c6CCCC7)cc5)CC4)CC3)ccc2C1=O
InChIKey LMHDKCMDVMZRMD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 758.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.05 6.05 6.05 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.72 5.72 5.73 ChEMBL
H3 HRH3 Human Histamine A pKi 7.13 7.13 7.14 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.97 5.98 5.98 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.66 5.66 5.66 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.28 6.29 6.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database