CHEMBL5465171


SMILES O=C1CCC(N2Cc3cc(C4CCN(C(=O)CCCCCN5CCC(c6ccc(Oc7nn8cnnc8c8c7CCCC8)cc6)CC5)CC4)ccc3C2=O)C(=O)N1
InChIKey HLNCBKSDCCIOPT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 772.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.25 6.25 6.25 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 6.2 6.21 6.21 ChEMBL
H3 HRH3 Human Histamine A pKi 7.14 7.14 7.15 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.17 6.17 6.17 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.78 5.78 5.78 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.64 5.66 5.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database