CHEMBL5433301


SMILES Cc1ccc([C@H](NC2=NS(=O)(=O)N=C2Nc2ccc(C)c(C(=O)N(C)C)c2O)C(C)(C)C)o1
InChIKey MAYXLCLBDVEYAL-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 475.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 6QZH

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR7 CCR7 Human Chemokine A pKi 7.0 7.08 7.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR7 CCR7 Human Chemokine A pIC50 5.14 5.91 7.46 ChEMBL
CXCR2 CXCR2 Human Chemokine A pIC50 5.19 5.19 5.19 ChEMBL