CHEMBL5429826


SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1)c1ccnc2ccccc12
InChIKey SBWDEIFOMNBGRY-MEMLXQNLSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 510.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.86 5.86 5.86 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.19 6.19 6.19 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.74 6.74 6.74 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.18 9.18 9.18 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.74 5.74 5.74 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.54 7.54 7.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database