CHEMBL5427695


SMILES COc1cccc(N2CCN(CC[C@H]3CC[C@H](NC(=O)N(C)C)CC3)CC2)c1F
InChIKey MUUSXXFKLPMJKL-IYARVYRRSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 406.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.47 7.47 7.47 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.47 7.47 7.47 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.03 8.03 8.03 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.87 6.87 6.87 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 8.79 8.79 8.79 ChEMBL
D2 DRD2 Human Dopamine A pEC50 8.39 8.98 9.57 ChEMBL