CHEMBL5423260


SMILES CC(C)[C@H]1CC[C@@H](N2CCC(n3c(CNS(N)(=O)=O)cc4ccccc43)CC2)CC1
InChIKey ODTGXINNSNOMFG-PUZFROQSSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 432.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.15 9.15 9.15 ChEMBL
δ OPRD Human Opioid A pKi 6.0 6.0 6.0 ChEMBL
κ OPRK Human Opioid A pKi 7.68 7.68 7.68 ChEMBL
μ OPRM Human Opioid A pKi 9.18 9.18 9.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.31 7.31 7.31 ChEMBL
μ OPRM Human Opioid A pEC50 7.18 7.18 7.18 ChEMBL