CHEMBL5419235


SMILES CCOC(=O)NCc1cc2ccccc2n1C1CCN([C@H]2CC[C@@H](C(C)C)CC2)CC1
InChIKey WMQOWAAURKEWQE-GRGXKFILSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 425.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.63 8.63 8.63 ChEMBL
δ OPRD Human Opioid A pKi 7.29 7.29 7.29 ChEMBL
κ OPRK Human Opioid A pKi 6.39 6.39 6.39 ChEMBL
μ OPRM Human Opioid A pKi 7.6 7.6 7.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.75 7.75 7.75 ChEMBL
δ OPRD Human Opioid A pEC50 6.54 6.54 6.54 ChEMBL
μ OPRM Human Opioid A pEC50 7.14 7.14 7.14 ChEMBL