CHEMBL5418283


SMILES COc1ccc(N2CCN(CCCCNC(=O)c3n[nH]c4ccccc34)CC2)cc1
InChIKey AOGNXLLKMCJHMU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 407.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 5.88 5.88 5.88 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.74 5.74 5.74 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.08 6.08 6.08 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.15 6.15 6.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database