CHEMBL5415010


SMILES CC(C)[C@H]1CC[C@@H](N2CCC(n3c(CN4CCS(=O)(=O)CC4)cc4ccccc43)CC2)CC1
InChIKey KRRSADFNAHKWFQ-QUPDYRNUSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 471.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.23 9.23 9.23 ChEMBL
δ OPRD Human Opioid A pKi 5.77 5.77 5.77 ChEMBL
κ OPRK Human Opioid A pKi 7.49 7.49 7.49 ChEMBL
μ OPRM Human Opioid A pKi 7.41 7.41 7.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.28 7.28 7.28 ChEMBL
μ OPRM Human Opioid A pEC50 7.42 7.42 7.42 ChEMBL