CHEMBL5414435


SMILES COc1cc([C@@H](C)C(=O)N2CC[C@@]3(COc4cc(-c5nc(C(F)(F)F)n(C)n5)c(C)nc4N3)C2)c(F)cn1
InChIKey SYULZWFVMLMMHI-SPSFWMDKSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 535.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pKi 9.35 9.35 9.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pIC50 8.08 8.08 8.08 ChEMBL