CHEMBL5412738


SMILES CC(=O)NCc1cc2ccccc2n1C1CCN([C@H]2CC[C@@H](C(C)C)CC2)CC1
InChIKey VEFKNVILUVRTOC-GRGXKFILSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 395.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.8 8.8 8.8 ChEMBL
δ OPRD Human Opioid A pKi 7.09 7.09 7.09 ChEMBL
κ OPRK Human Opioid A pKi 6.75 6.75 6.75 ChEMBL
μ OPRM Human Opioid A pKi 7.61 7.61 7.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.3 7.3 7.3 ChEMBL
δ OPRD Human Opioid A pEC50 6.87 6.87 6.87 ChEMBL
μ OPRM Human Opioid A pEC50 6.95 6.95 6.95 ChEMBL