CHEMBL5404274


SMILES CC(C)[C@H]1CC[C@@H](N2CCC(n3c(CCO)cc4ccccc43)CC2)CC1
InChIKey IOGDKVPBHYKTLL-TYKWCNGQSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 368.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.03 9.03 9.03 ChEMBL
δ OPRD Human Opioid A pKi 6.81 6.81 6.81 ChEMBL
κ OPRK Human Opioid A pKi 7.29 7.29 7.29 ChEMBL
μ OPRM Human Opioid A pKi 7.69 7.69 7.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.5 7.5 7.5 ChEMBL
μ OPRM Human Opioid A pEC50 7.14 7.14 7.14 ChEMBL