CHEMBL5403724


SMILES CC(C)[C@H]1CC[C@@H](N2CCC(n3c(CO)cc4ccccc43)CC2)CC1
InChIKey MNCLQFXBMWGDDJ-PUZFROQSSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 354.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.47 9.47 9.47 ChEMBL
δ OPRD Human Opioid A pKi 6.89 6.89 6.89 ChEMBL
κ OPRK Human Opioid A pKi 7.14 7.14 7.14 ChEMBL
μ OPRM Human Opioid A pKi 8.22 8.22 8.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.52 7.52 7.52 ChEMBL
δ OPRD Human Opioid A pEC50 5.34 5.34 5.34 ChEMBL
μ OPRM Human Opioid A pEC50 7.09 7.09 7.09 ChEMBL