CHEMBL5403268


SMILES COCCC(=O)N[C@H]1CC[C@H](CCN2CCN(c3cccc(OC)c3F)CC2)CC1
InChIKey SVPFZRJDQVOOKQ-WGSAOQKQSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 421.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.13 6.13 6.13 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.53 7.53 7.53 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.16 7.16 7.16 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.88 8.88 8.88 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.32 6.32 6.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 8.54 8.54 8.54 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.96 8.54 9.13 ChEMBL