CHEMBL5270265


SMILES CC1CCCN1CCCOc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](N3CCCC3)CC[C@@H]12
InChIKey BLISAYWDMSAMTN-OKSFETJPSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 450.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 8.44 8.44 8.44 ChEMBL
H3 HRH3 Human Histamine A pKi 9.3 9.3 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pIC50 7.92 7.92 7.92 ChEMBL
H3 HRH3 Human Histamine A pEC50 9.4 9.4 9.4 ChEMBL