CHEMBL495744


SMILES c1cc(CN2CCOCC2)cc(OCC2CN(C3CCC3)CCO2)c1
InChIKey NIPMSTUGWAGNHI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 346.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 6.56 6.56 6.56 ChEMBL
H3 HRH3 Rat Histamine A pKd 7.1 7.1 7.1 ChEMBL
H3 HRH3 Human Histamine A pKi 7.43 7.43 7.43 ChEMBL
H3 HRH3 Human Histamine A pKd 7.85 7.85 7.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database