CHEMBL4877940


SMILES COc1cc(CN2CCCC2)ccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1
InChIKey IHWMDXVSMHTLOY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 467.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 6.82 6.82 6.82 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.11 7.11 7.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.97 7.97 7.97 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.21 8.21 8.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database