CHEMBL4870307


SMILES COc1cc(CN2CCCCC2)ccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1
InChIKey XJPIMYAKYUJUQV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 481.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 6.59 6.59 6.59 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.17 7.17 7.17 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.05 8.05 8.05 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.02 8.02 8.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database