CHEMBL4853342


SMILES Fc1ccc2c(C3CCN(CCCOc4ccc(CN5CCOCC5)cc4Cl)CC3)noc2c1
InChIKey LJDQVOLRQLNUCX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 487.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 6.83 6.83 6.83 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.98 6.98 6.98 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.24 8.24 8.24 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.6 8.6 8.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database