DERSIMELAGON


SMILES COC[C@H]1CN(C(=O)[C@]2(F)CN(C3CCCC3)C[C@H]2c2ccc(OC)cc2)C[C@@H]1c1ccc(C(F)(F)F)cc1N1CCC(C(=O)O)CC1
InChIKey MUNWOYRHJPWQNE-GMFUQMJFSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 675.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pKi 6.31 6.31 6.31 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.48 7.48 7.48 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.85 5.85 5.85 ChEMBL
MC1 MSHR Human Melanocortin A pKi 8.64 8.64 8.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pEC50 7.1 7.1 7.1 ChEMBL
MC1 MSHR Human Melanocortin A pEC50 8.09 8.09 8.09 ChEMBL