GHRP-6
| SMILES | NCCCCC(C(=O)N)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)C(NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)C(Cc1cnc[nH]1)N)C |
| InChIKey | WZHKXNSOCOQYQX-UHFFFAOYSA-N |
| Sequence | HWAWFK |
Chemical properties
| Hydrogen bond acceptors | 9 |
| Hydrogen bond donors | 11 |
| Rotatable bonds | 23 |
| Molecular weight (Da) | 872.4 |
Drug properties
| Molecular type | Peptide |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
| Structure pdb | 7F9Z |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| ghrelin | GHSR | Human | Ghrelin | A | pKd | 6.6 | 7.7 | 8.8 | Guide to Pharmacology |
| ghrelin | GHSR | Rat | Ghrelin | A | pKi | 8.8 | 8.8 | 8.8 | Guide to Pharmacology |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| ghrelin | GHSR | Human | Ghrelin | A | pEC50 | 8.71 | 8.71 | 8.71 | Guide to Pharmacology |