CHEMBL4781390


SMILES CN1CCc2ccc(OCCCCN3CCN(c4cccc(C(F)(F)F)c4)CC3)cc2C1=O
InChIKey NWSWBVKRQJZUCZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 461.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.58 6.58 6.58 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.98 6.96 7.93 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.76 7.76 7.76 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.63 7.63 7.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database