CHEMBL4777373


SMILES CN1CCc2ccc(OCCCN3CCN(c4ccccc4F)CC3)cc2C1=O
InChIKey JSYJUUGAOMCCSL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 397.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.93 6.93 6.93 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.58 7.1 7.61 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.26 7.26 7.26 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.52 7.52 7.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database