CHEMBL4761213


SMILES CN1CCc2ccc(OCCCN3CCN(c4ncccn4)CC3)cc2C1=O
InChIKey SKUUWDIJGSUACY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 381.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 5.86 5.86 5.86 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.23 7.65 8.06 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.92 7.92 7.92 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database