galanin(2-29) (pig)


SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)O
InChIKey GGBMOXFFZWACOW-QTRPWDSUSA-N
Sequence WTLNSAGYLLGPHAIDNHRSFHDKYGLA

Chemical properties

Hydrogen bond acceptors 43
Hydrogen bond donors 44
Rotatable bonds 97
Molecular weight (Da) 3152.6

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL2 GALR2 Human Galanin A pKi 8.54 8.54 8.54 Guide to Pharmacology
GAL3 GALR3 Human Galanin A pKi 7.22 7.22 7.22 Guide to Pharmacology
GAL1 GALR1 Rat Galanin A pKi 7.08 7.62 8.15 Guide to Pharmacology
GAL1 GALR1 Human Galanin A pKi 7.58 7.58 7.58 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL2 GALR2 Human Galanin A pEC50 7.62 8.28 8.93 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pIC50 8.73 8.73 8.74 Guide to Pharmacology
GAL1 GALR1 Human Galanin A pIC50 7.52 7.52 7.52 Guide to Pharmacology