galanin(2-11)


SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)NCC(=O)O
InChIKey MUEGHULZMXFVFL-ZHRZWFTASA-N
Sequence WTLNSAGYLLG

Chemical properties

Hydrogen bond acceptors 16
Hydrogen bond donors 17
Rotatable bonds 35
Molecular weight (Da) 1193.6

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL1 GALR1 Human Galanin A pKi 5.3 5.3 5.3 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pKi 7.78 7.78 7.78 Guide to Pharmacology
GAL3 GALR3 Human Galanin A pKi 6.7 6.7 6.7 Guide to Pharmacology
GAL3 GALR3 Rat Galanin A pKi 6.57 6.57 6.57 Guide to Pharmacology
GAL2 GALR2 Rat Galanin A pKi 7.06 7.06 7.06 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL1 GALR1 Human Galanin A pIC50 6.06 6.06 6.06 Guide to Pharmacology
GAL2 GALR2 Rat Galanin A pIC50 8.75 8.75 8.75 Guide to Pharmacology