CHEMBL4746373


SMILES CCN1CCc2ccc(OCCCN3CCC(c4noc5cc(F)ccc45)CC3)cc2C1=O
InChIKey NGSZJZCWVNVBQV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 451.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.6 6.6 6.6 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.7 7.71 8.72 ChEMBL
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.9 7.9 7.9 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.88 7.88 7.88 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database