CHEMBL472811


SMILES COc1ccccc1N1CCN(CCCON2C(=O)C3C4C=CC(OC)(CC4)C3C2=O)CC1
InChIKey UIPXVRQAUIPYIL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 455.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.86 5.86 5.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database