CHEMBL4519837


SMILES CC(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O)C(C)C
InChIKey RFBVPLQWBKNMQV-XUJYPJAKSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 7
Rotatable bonds 14
Molecular weight (Da) 654.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Mouse Melanocortin A pKd 6.2 6.2 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 7.28 7.34 7.4 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 9.22 9.46 9.7 ChEMBL
MC4 MC4R Mouse Melanocortin A pEC50 6.4 6.61 6.82 ChEMBL