CHEMBL448825


SMILES c1cc(OCC2CN(C3CCCC3)CCO2)ccc1CN1CCOCC1
InChIKey CCLHRWBVZOMXEV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 360.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.7 7.7 7.7 ChEMBL
H3 HRH3 Rat Histamine A pKd 8.32 8.32 8.32 ChEMBL
H3 HRH3 Human Histamine A pKi 8.44 8.44 8.44 ChEMBL
H3 HRH3 Human Histamine A pKd 9.02 9.02 9.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database