CHEMBL4208452


SMILES Fc1cccc(Cc2ccnc3c2CC[C@@H]2CNCCN32)c1
InChIKey LXJQUSCIXJJMCJ-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 297.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.78 7.78 7.78 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.71 6.71 6.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.43 7.43 7.43 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 6.94 6.94 6.94 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 9.72 9.72 9.72 ChEMBL