ORM-13070


SMILES COCc1cccnc1N1CCN(C[C@H]2COc3ccccc3O2)CC1
InChIKey VGIYMYGMVXPMKV-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 355.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKd 7.64 7.64 7.64 ChEMBL
α2C ADA2C Human Adrenoceptors A pKd 8.42 8.42 8.42 ChEMBL
α2A ADA2A Human Adrenoceptors A pKd 6.96 6.96 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database