CHEMBL4092125


SMILES CN1CCc2ccccc2C1CNC(=O)c1ccc(Cl)c(Cl)c1
InChIKey LIYLICKKTYEDQP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 348.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 8.16 8.16 8.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 9.77 9.77 9.77 ChEMBL
κ OPRK Human Opioid A pIC50 6.36 6.36 6.36 ChEMBL
μ OPRM Human Opioid A pEC50 8.0 8.0 8.0 ChEMBL
μ OPRM Human Opioid A pIC50 7.3 7.3 7.3 ChEMBL