d[Pen1,Tyr(Me)2]AVP


SMILES COc1ccc(cc1)CC1NC(=O)CC(C)(C)SSCC(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)Cc1ccccc1)CCC(=O)N)CC(=O)N)C(=O)N1CCCC1C(=O)NC(C(=O)NCC(=O)N)CCCN=C(N)N
InChIKey HNOGCDKPALYUIG-UHFFFAOYSA-N
Sequence XYFQNCPRG

Chemical properties

Hydrogen bond acceptors 15
Hydrogen bond donors 12
Rotatable bonds 20
Molecular weight (Da) 1110.5

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Human Vasopressin and oxytocin A pKi 9.1 9.1 9.1 Guide to Pharmacology
V1B V1BR Human Vasopressin and oxytocin A pKi 8.2 8.2 8.2 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKi 6.4 6.55 6.7 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database