DOM


SMILES COc1cc(C)c(cc1CC(N)C)OC
InChIKey NTJQREUGJKIARY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 209.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Ligand site mutations 5-HT2A

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 Guide to Pharmacology
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 7.12 7.12 7.12 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.71 6.71 6.71 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 5.68 5.68 5.68 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.29 5.29 5.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database